Relationship between methylation of the p15 gene in myelodysplastic syndromes (MDS)
نویسندگان
چکیده
منابع مشابه
Hypermethylation of the p15 Gene in Myelodysplastic Syndromes
Previous studies have shown that the cyclin-dependent kiterestingly, the p15 gene was frequently methylated in patients with high-risk MDS (refractory anemia with excess nase inhibitor (CDKI) genes p15 and p16 are frequently inactivated by genetic alterations in many malignant blasts [RAEB], RAEB in transformation [RAEB-t], and overt leukemia evolved from MDS; 14/18 [78%]) compared with tumors ...
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Forty two patients who were seen and satisfied the French-American-British (FAB) diagnostic criteria for myelodysplastic syndromes (MDS) over a 6-year period at the University of Zimbabwe's Department of Haematology, Harare, are presented. Their overall ages ranged from 29 to 75 years with a mean +/- SD of 57.8 +/- 11.2 years. Males outnumbered females with a male to female ratio of 1.2:1. Refr...
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Twenty three Zimbabwean African patients who satisfied the French-American-British(FAB) diagnostic criteria for the myelodysplastic syndromes(MDS) at Godfrey Huggins School of Medicine, University of Zimbabwe, between July 1985 and June 1987 are presented. The disorders appear not to behave differently from those reported in Caucasian populations with regard to clinical and haematological featu...
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ژورنال
عنوان ژورنال: Leukemia
سال: 2001
ISSN: 0887-6924,1476-5551
DOI: 10.1038/sj.leu.2402138